Endocrine Abstracts

Opioid analgesia impairs gonadal function in healthy men and women. Methadone, a synthetic opioid is used in opioid addicts to prevent relapse due its longer-lasting effects and is known to cause hypogonadism. Little data exists on the prevalence of this and the mechanism through which this occurs.Men (n=147), mean age 36.2 years (S.D 7.2) attending a drug-treatment rehabilitation centre for methadone maintenance therapy had early m...

Thyroid Doppler ultrasound (TDUS) is highly used in the evaluation of thyroid nodules (TN). Malignant thyroid pathology has been more frequently associated with central vascularization of such nodules. There is controversy regarding the usefulness of the Resistance Index (RI) in the assessment of TN.Our aim was to analyze the utility of vascularization characteristics and RI at TDUS in the distinction of benign and malignant TN.Mat...

It is important to know the prevalence of common diseases in every country in order to guide us to take decisions regarding public health benefits in screening, in Mexico we do not have information regarding thyroid abnormalities.Methods: We designed a cross-sectional study in the city of Queretaro (Mexico) in order to know the prevalence of altered thyroid function tests in our population, since we do not have any previous study. We calculated the sampl...